BDBM571574 3-acetyl-1-(2-((2S,4R)-2- ((6-bromopyridin-2- yl)carbamoyl)-4- fluoropyrrolidin-1-yl)-2- oxoethyl)-N-(thiazol-4- ylmethyl)-1H-pyrazole-5- carboxamide::US11447465, Cmp No. T-24

SMILES CC(=O)c1cc(C(=O)NCc2cscn2)n(CC(=O)N2C[C@H](F)C[C@H]2C(=O)Nc2cccc(Br)n2)n1

InChI Key InChIKey=PKVFNCIPSUAZCE-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 571574   

TargetComplement factor D(Human)
Achillion Pharmaceuticals

US Patent
LigandPNGBDBM571574(3-acetyl-1-(2-((2S,4R)-2- ((6-bromopyridin-2- yl)c...)
Affinity DataIC50: 1.00E+3nMAssay Description:Human Factor D (purified from human serum, Complement Technology, Inc.) at 80 nM final concentration is incubated with test compound at various conce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2022
Entry Details
US Patent