BDBM571592 (3-acetyl-1-(2- ((1R,3S,5R)-3-((3-chloro- 2- fluorobenzyl)carbamoyl)- 5-((4-methylpiperazin-1- yl)methyl)-2- azabicyclo[3.1.0]hexan-2- yl)-2-oxoethyl)-1H-indol- 6-yl)phosphonic acid::US11447465, Cmp No. T-44

SMILES CN1CCN(C[C@]23C[C@H]2N([C@@H](C3)C(=O)NCc2cccc(Cl)c2F)C(=O)Cn2nc(C(C)=O)c3ccc(cc23)P(O)(O)=O)CC1

InChI Key InChIKey=HVSQJTRITHYIOT-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 571592   

TargetComplement factor D(Human)
Achillion Pharmaceuticals

US Patent
LigandPNGBDBM571592((3-acetyl-1-(2- ((1R,3S,5R)-3-((3-chloro- 2- fluor...)
Affinity DataIC50: 1.00E+3nMAssay Description:Human Factor D (purified from human serum, Complement Technology, Inc.) at 80 nM final concentration is incubated with test compound at various conce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2022
Entry Details
US Patent