BDBM571975 US11447487, Example 68

SMILES NC(=O)c1cccnc1O[C@H]1CC2(C1)C[C@H](N1C(=O)NC(CC34CC5CC(CC(C5)C3)C4)C1=O)C2

InChI Key InChIKey=OJVXRIPDMJEYBL-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 571975   

TargetRho-associated protein kinase 2(Human)
Bristol Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 571975BDBM571975(US11447487, Example 68)
Affinity DataIC50: 17nMAssay Description:The effectiveness of compounds of the present invention as ROCK inhibitors can be determined in a 30 μL assay containing 20 mM HEPES, pH 7.5, 20...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2022
Entry Details
US Patent