BDBM571997 2-(((alphaR)-6-(4-((E)-2- methyl-3- phenylallyl)-2,5- dioxoimidazolidin- 1- yl)spiro[3.3]heptan- 2- yl)oxy)nicotinamide::US11447487, Example 90

SMILES C/C(=C\c1ccccc1)CC1NC(=O)N([C@H]2CC3(C[C@H](Oc4ncccc4C(N)=O)C3)C2)C1=O

InChI Key InChIKey=AXKTYWQNCHTHSU-UHFFFAOYSA-N

Data  1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 571997   

TargetRho-associated protein kinase 2(Human)
Bristol Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 571997BDBM571997(2-(((alphaR)-6-(4-((E)-2- methyl-3- phenylallyl)-2...)
Affinity DataIC50: 21nMAssay Description:The effectiveness of compounds of the present invention as ROCK inhibitors can be determined in a 30 μL assay containing 20 mM HEPES, pH 7.5, 20...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2022
Entry Details
US Patent