BDBM573192 US11453681, Compound C37

SMILES Cc1cc2c(cc1-c1cnc3c(c1C)NCCO3)/C(=C/c1cc3ccncc3[nH]1)C(=O)N2

InChI Key InChIKey=SLOBKXOOORRHCN-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 573192   

TargetMitogen-activated protein kinase kinase kinase kinase 1(Human)
Gilead Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 573192BDBM573192(US11453681, Compound C37)
Affinity DataIC50: 0.690nMAssay Description:The enzymatic activity of human HPK1 (MAP4K1) was monitored in a biochemical assay in the presence or absence of compounds and using a synthetic pept...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2022
Entry Details
US Patent