BDBM573214 US11453681, Compound C59

SMILES Cc1c(-c2ccc3c(c2)/C(=C/c2nc4ccccc4[nH]2)C(=O)N3)cnc2c1NCCO2

InChI Key InChIKey=AIAHUIPSXMOHNX-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 573214   

TargetMitogen-activated protein kinase kinase kinase kinase 1(Human)
Gilead Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 573214BDBM573214(US11453681, Compound C59)
Affinity DataIC50: 0.280nMAssay Description:The enzymatic activity of human HPK1 (MAP4K1) was monitored in a biochemical assay in the presence or absence of compounds and using a synthetic pept...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2022
Entry Details
US Patent