BDBM573930 2-amino-9- [(5R,7R,8R,12aR,14R,15R,15aS,18S)-14-(6- amino-9H-purin-9-yl)-2,10,18-trihydroxy-2,10- disulfidohexahydro-14H-15,12a- (epoxymethano)-5,8-methanofuro[3,2- l][1,3,9,11,6,2,10] tetraoxathiadiphosphacyclotetradecin- 7(12H)-yl]-1,9-dihydro-6H-purin-6-one (Diastereomer 1)::US11453697, Example 100::US11453697, Example 101::US11453697, Example 102
SMILES Nc1nc2n(cnc2c(=O)[nH]1)[C@@H]1S[C@@H]2COP(O)(=S)O[C@H]3[C@H]4OC[C@]3(COP(O)(=S)O[C@@H]1[C@@H]2O)O[C@H]4n1cnc2c(N)ncnc12
InChI Key InChIKey=LMROVXZRLJWFSS-UHFFFAOYSA-N
Data 6 EC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 573930
TargetStimulator of interferon genes protein [1-379,R71H,G230A,H232R,R293Q](Human)
Merck Sharp & Dohme
US Patent
Merck Sharp & Dohme
US Patent
Affinity DataEC50: <1nMAssay Description:The compounds were serially titrated by the Hamilton STARPlus CORE in a 96-well plate (Greiner, #651201) using a 1:3 ten-point dose response format. ...More data for this Ligand-Target Pair
TargetStimulator of interferon genes protein [1-379,R71H,G230A,H232R,R293Q](Human)
Merck Sharp & Dohme
US Patent
Merck Sharp & Dohme
US Patent
Affinity DataEC50: 8nMAssay Description:The compounds were serially titrated by the Hamilton STARPlus CORE in a 96-well plate (Greiner, #651201) using a 1:3 ten-point dose response format. ...More data for this Ligand-Target Pair
TargetStimulator of interferon genes protein [1-379,R71H,G230A,H232R,R293Q](Human)
Merck Sharp & Dohme
US Patent
Merck Sharp & Dohme
US Patent
Affinity DataEC50: 16.7nMAssay Description:The compounds were serially titrated by the Hamilton STARPlus CORE in a 96-well plate (Greiner, #651201) using a 1:3 ten-point dose response format. ...More data for this Ligand-Target Pair