BDBM573949 2-amino-9- [(5R,7R,8S,12aR,14R,15R,15aS,18R)-14-(6- amino-9H-purin-9-yl)-18-fluoro-2,10-dioxido- 2,10-disulfanylhexahydro-14H-15,12a- (epoxymethano)-5,8-methanofuro[3,2-l] [1,3,6,9,11,2,10]pentaoxadiphosphacyclotetra- decin-7(12H)-yl]-1,9-dihydro-6H-purin-6-one (Diastereomer 1)::US11453697, Example 134::US11453697, Example 135::US11453697, Example 136::US11453697, Example 137

SMILES Nc1nc2n(cnc2c(=O)[nH]1)[C@@H]1O[C@@H]2COP(S)(=O)O[C@H]3[C@H]4OCC3(COP(S)(=O)O[C@@H]1[C@@H]2F)O[C@H]4n1cnc2c(N)ncnc12

InChI Key InChIKey=VIQFEYGWWKNVAI-UHFFFAOYSA-N

Data  4 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 573949   

LigandPNGBDBM573949(US11453697, Example 134 | US11453697, Example 136 ...)
Affinity DataEC50: <1nMAssay Description:The compounds were serially titrated by the Hamilton STARPlus CORE in a 96-well plate (Greiner, #651201) using a 1:3 ten-point dose response format. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2022
Entry Details
US Patent

LigandPNGBDBM573949(US11453697, Example 134 | US11453697, Example 136 ...)
Affinity DataEC50:  3.70nMAssay Description:The compounds were serially titrated by the Hamilton STARPlus CORE in a 96-well plate (Greiner, #651201) using a 1:3 ten-point dose response format. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2022
Entry Details
US Patent

LigandPNGBDBM573949(US11453697, Example 134 | US11453697, Example 136 ...)
Affinity DataEC50:  11.4nMAssay Description:The compounds were serially titrated by the Hamilton STARPlus CORE in a 96-well plate (Greiner, #651201) using a 1:3 ten-point dose response format. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2022
Entry Details
US Patent

LigandPNGBDBM573949(US11453697, Example 134 | US11453697, Example 136 ...)
Affinity DataEC50:  253nMAssay Description:The compounds were serially titrated by the Hamilton STARPlus CORE in a 96-well plate (Greiner, #651201) using a 1:3 ten-point dose response format. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2022
Entry Details
US Patent