BDBM573985 2-amino-9- [(5R,7R,8S,12aR,14R,15S,15aR,16R)- 15,16-difluoro-2,10-dihydroxy-10-oxido- 14-(6-oxo-1,6-dihydro-9H-purin-9-yl)-2- sulfidooctahydro-12H-5,8- methanofuro[3,2-l][1,3,6,9,11,2,10] pentaoxadiphosphacyclotetradecin-7-yl]- 1,9-dihydro-6H-purin-6-one::US11453697, Example 303

SMILES Nc1nc2n(cnc2c(=O)[nH]1)[C@@H]1O[C@@H]2COP(O)(=S)O[C@@H]3[C@@H](COP(O)(=O)O[C@@H]1[C@@H]2F)O[C@H]([C@H]3F)n1cnc2c1nc[nH]c2=O

InChI Key InChIKey=RGZUYVDJRCKNES-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 573985   

LigandPNGBDBM573985(US11453697, Example 303 | 2-amino-9- [(5R,7R,8S,12...)
Affinity DataEC50: <1nMAssay Description:The compounds were serially titrated by the Hamilton STARPlus CORE in a 96-well plate (Greiner, #651201) using a 1:3 ten-point dose response format. ...More data for this Ligand-Target Pair
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Date in BDB:
12/4/2022
Entry Details
US Patent