BDBM573989 2-amino-9-[(2R,5R,7R,8S,10R, 12aR,14R,15aS,16R)-16-fluoro-2,10- dihydroxy-14-(6-oxo-1,6-dihydro-9H- purin-9-yl)-2,10-disulfidooctahydro-12H- 5,8-methanofuro[3,2-l][1,3,6,9,11,2,10] pentaoxadiphosphacyclotetradecin-7-yl]- 1,9-dihydro-6H-purin-6-one (Diastereomer 3)::US11453697, Example 307

SMILES Nc1nc2n(cnc2c(=O)[nH]1)[C@@H]1O[C@@H]2CO[P@](S)(=O)O[C@H]3C[C@@H](O[C@@H]3CO[P@](S)(=O)O[C@@H]1[C@@H]2F)n1cnc2c1nc[nH]c2=O

InChI Key InChIKey=PTDCVKCXYWZLHS-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 573989   

LigandPNGBDBM573989(US11453697, Example 307 | 2-amino-9-[(2R,5R,7R,8S,...)
Affinity DataEC50: <1nMAssay Description:The compounds were serially titrated by the Hamilton STARPlus CORE in a 96-well plate (Greiner, #651201) using a 1:3 ten-point dose response format. ...More data for this Ligand-Target Pair
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Date in BDB:
12/4/2022
Entry Details
US Patent