BDBM574021 5-amino-3-[(5R,7R,8R,12aR,14R,15aS,16S)-14- (4-aminoimidazo[2,1-f][1,2,4]triazin-7-yl)-16- hydroxy-2,10-dioxido-2,10-disulfanyloctahydro- 12H-5,8-methanofuro[3,2-l][1,3,9,11,6,2,10] tetraoxathiadiphosphacyclotetradecin-7-yl]-3,6- dihydro-7H-[1,2,3]triazolo[4,5-d] pyrimidin-7-one (Diastereomer 1)::US11453697, Example 111::US11453697, Example 112::US11453697, Example 113::US11453697, Example 114

SMILES Nc1nc2n(nnc2c(=O)[nH]1)[C@@H]1S[C@@H]2COP(S)(=O)O[C@H]3C[C@@H](O[C@@H]3COP(S)(=O)O[C@@H]1[C@@H]2O)c1cnc2c(N)ncnn12

InChI Key InChIKey=ICLHYBHGTNLLJU-UHFFFAOYSA-N

Data  4 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 574021   

TargetStimulator of interferon genes protein [H232R](ZEBOV)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM574021(US11453697, Example 111 | US11453697, Example 114 ...)
Affinity DataEC50:  3.30nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2022
Entry Details
US Patent

TargetStimulator of interferon genes protein [H232R](ZEBOV)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM574021(US11453697, Example 111 | US11453697, Example 114 ...)
Affinity DataEC50:  44.2nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2022
Entry Details
US Patent

TargetStimulator of interferon genes protein [H232R](ZEBOV)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM574021(US11453697, Example 111 | US11453697, Example 114 ...)
Affinity DataEC50:  155nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2022
Entry Details
US Patent

TargetStimulator of interferon genes protein [H232R](ZEBOV)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM574021(US11453697, Example 111 | US11453697, Example 114 ...)
Affinity DataEC50:  1.28E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2022
Entry Details
US Patent