BDBM574086 2-amino-9- [(5R,7R,8R,12aR,14R,15S,15aR,16S)- 14-(6-amino-9H-purin-9-yl)-15,16-difluoro-2,10- dioxido-2,10-disulfanyloctahydro- 12H-5,8-methanofuro[3,2- l][1,3,6,9,11,2,10]tetraoxathiadiphosphacyclo- tetradecin-7-yl]-1,9-dihydro-6H-purin-6-one (Diastereomer 1)::US11453697, Example 214::US11453697, Example 215::US11453697, Example 216::US11453697, Example 217

SMILES Nc1nc2n(cnc2c(=O)[nH]1)[C@@H]1S[C@@H]2COP(S)(=O)O[C@@H]3[C@@H](COP(S)(=O)O[C@@H]1[C@@H]2F)O[C@H]([C@H]3F)n1cnc2c(N)ncnc12

InChI Key InChIKey=AAOIOCAYCBHKDO-UHFFFAOYSA-N

Data  4 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 574086   

TargetStimulator of interferon genes protein [H232R](ZEBOV)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM574086(US11453697, Example 214 | US11453697, Example 217 ...)
Affinity DataEC50:  2.10nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2022
Entry Details
US Patent

TargetStimulator of interferon genes protein [H232R](ZEBOV)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM574086(US11453697, Example 214 | US11453697, Example 217 ...)
Affinity DataEC50:  3.40nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2022
Entry Details
US Patent

TargetStimulator of interferon genes protein [H232R](ZEBOV)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM574086(US11453697, Example 214 | US11453697, Example 217 ...)
Affinity DataEC50:  33.1nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2022
Entry Details
US Patent

TargetStimulator of interferon genes protein [H232R](ZEBOV)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM574086(US11453697, Example 214 | US11453697, Example 217 ...)
Affinity DataEC50:  66.2nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2022
Entry Details
US Patent