BDBM574116 2-amino-9-[(5R,7R,8S,12aR,14R,15aS,16R)-14- (4-aminoimidazo[2,1-f][1,2,4]triazin-7-yl)-16- fluoro-2,10-dioxido-2,10-disulfanyloctahydro- 12H-5,8-methanofuro[3,2- 1][1,3,6,9,11,2,10]pentaoxadiphosphacyclotetra- decin-7-yl]-1,9-dihydro-6H-purin-6-one (Diastereomer 1)::US11453697, Example 248::US11453697, Example 249::US11453697, Example 250::US11453697, Example 251

SMILES Nc1nc2n(cnc2c(=O)[nH]1)[C@@H]1O[C@@H]2COP(S)(=O)O[C@H]3C[C@@H](O[C@@H]3COP(S)(=O)O[C@@H]1[C@@H]2F)c1cnc2c(N)ncnn12

InChI Key InChIKey=GZNFCNNBSNXFCO-UHFFFAOYSA-N

Data  4 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 574116   

TargetStimulator of interferon genes protein [H232R](ZEBOV)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM574116(US11453697, Example 248 | US11453697, Example 249 ...)
Affinity DataEC50: <1nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2022
Entry Details
US Patent

TargetStimulator of interferon genes protein [H232R](ZEBOV)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM574116(US11453697, Example 248 | US11453697, Example 249 ...)
Affinity DataEC50: <1nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2022
Entry Details
US Patent

TargetStimulator of interferon genes protein [H232R](ZEBOV)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM574116(US11453697, Example 248 | US11453697, Example 249 ...)
Affinity DataEC50:  17.3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2022
Entry Details
US Patent

TargetStimulator of interferon genes protein [H232R](ZEBOV)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM574116(US11453697, Example 248 | US11453697, Example 249 ...)
Affinity DataEC50:  31.7nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2022
Entry Details
US Patent