BDBM574482 US11458149, Compound I-35

SMILES CN(c1cccc(c1)C(F)(F)F)c1cc(NC(=O)C=C)ccc1C

InChI Key InChIKey=ZEACEPHIHVXUED-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 574482   

TargetTranscriptional enhancer factor TEF-1(Human)
Ikena Oncology

US Patent
LigandPNGBDBM574482(US11458149, Compound I-35)
Affinity DataEC50: <100nMAssay Description:TEAD inhibition can be assayed using Hippo Pathway TEAD Reporter—MCF7 Cell Line (BPS Bioscience, Catalog #: 60618).More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent