BDBM575437 US11459337, Compound WX006

SMILES Cc1nsc2nc(Nc3cnn([C@H]4CCOC4)c3)nc(N[C@H]3CC[C@H](N4CCOCC4)CC3)c12

InChI Key InChIKey=SLGDPCANBLQLJD-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 575437   

TargetInterleukin-1 receptor-associated kinase 4(Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandChemical structure of BindingDB Monomer ID 575437BDBM575437(US11459337, Compound WX006)
Affinity DataIC50: 9.90nMAssay Description:The inhibitory activity of the test compounds against human IRAK4 was evaluated by measuring IC50 values in a 33P-labeled kinase activity assay (Reac...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2022
Entry Details
US Patent