BDBM575456 US11459337, Compound WX034

SMILES COC(=O)N1CCN([C@H]2CC[C@H](Nc3nc(Nc4cnn([C@H]5CCOC5)c4)nc4snc(C)c34)CC2)CC1

InChI Key InChIKey=OUBIZVWIDQNBOH-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 575456   

TargetInterleukin-1 receptor-associated kinase 4(Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandChemical structure of BindingDB Monomer ID 575456BDBM575456(US11459337, Compound WX034)
Affinity DataIC50: 12.8nMAssay Description:The inhibitory activity of the test compounds against human IRAK4 was evaluated by measuring IC50 values in a 33P-labeled kinase activity assay (Reac...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2022
Entry Details
US Patent