BDBM575462 US11459337, Compound WX040

SMILES Cc1nsc2nc(Nc3cnn(C4CCOCC4)c3)nc(N[C@H]3CC[C@H](N4CC5CC(C4)N5)CC3)c12

InChI Key InChIKey=SYIKAOROWLEBBF-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 575462   

TargetInterleukin-1 receptor-associated kinase 4(Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandChemical structure of BindingDB Monomer ID 575462BDBM575462(US11459337, Compound WX040)
Affinity DataIC50: 30nMAssay Description:The inhibitory activity of the test compounds against human IRAK4 was evaluated by measuring IC50 values in a 33P-labeled kinase activity assay (Reac...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2022
Entry Details
US Patent