BDBM575465 US11459337, Compound WX044

SMILES COC(=O)N1C2CC1CN([C@H]1CC[C@H](Nc3nc(Nc4cnn(C5CCOCC5)c4)nc4snc(C)c34)CC1)C2

InChI Key InChIKey=ZSPDLYQGHLLQFX-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 575465   

TargetInterleukin-1 receptor-associated kinase 4(Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandChemical structure of BindingDB Monomer ID 575465BDBM575465(US11459337, Compound WX044)
Affinity DataIC50: 40.7nMAssay Description:The inhibitory activity of the test compounds against human IRAK4 was evaluated by measuring IC50 values in a 33P-labeled kinase activity assay (Reac...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2022
Entry Details
US Patent