BDBM575971 (1R,2S,3S,5S)-8-[7- (3,4-dichloro-2- methyl-2H-indazol- 5-yl)-5H- pyrrolo[2,3- b]pyrazin-3-yl]-2- fluoro-8- azabicyclo[3.2.1]oc- tan-3-amine, hydrochloride::US11466016, Example 104
SMILES Cn1nc2ccc(-c3n[nH]c4nc(cnc34)N3[C@H]4CC[C@@H]3[C@@H](F)[C@@H](N)C4)c(Cl)c2c1Cl
InChI Key
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 575971
Affinity DataIC50: 9.5nMAssay Description:SHP2 activity was monitored by measuring the conversion of the surrogate substrate 6,8-difluoromethylumbelliferyl phosphate (DiFMUP) to the fluoresce...More data for this Ligand-Target Pair