BDBM576115 N-(2-methyl-5-(6-methyl-7- oxo-6,7-dihydro-1H-pyrrolo [2,3-c]pyridin-4-yl)-3-(4- (trifluoromethyl)benzyl)-3H- imidazo[4,5-b]pyridin-7-yl) ethanesulfonamide::US11466034, Example 65

SMILES CCS(=O)(=O)Nc1cc(nc2n(Cc3ccc(cc3)C(F)(F)F)c(C)nc12)-c1cn(C)c(=O)c2[nH]ccc12

InChI Key InChIKey=DMKFCMUEVDTQSW-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 576115   

TargetBromodomain-containing protein 4 [44-167](Human)
Betta Pharmaceuticals

US Patent
LigandPNGBDBM576115(N-(2-methyl-5-(6-methyl-7- oxo-6,7-dihydro-1H-pyrr...)
Affinity DataIC50: 100nMAssay Description:The assays of BRD4 (D1) and BRD4 (D2) were conducted in a 384-well polystyrene plate. The test compounds were first serially diluted in DMSO and the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2022
Entry Details
US Patent

TargetBromodomain-containing protein 4 [349-460](Human)
Betta Pharmaceuticals

US Patent
LigandPNGBDBM576115(N-(2-methyl-5-(6-methyl-7- oxo-6,7-dihydro-1H-pyrr...)
Affinity DataIC50: 100nMAssay Description:The assays of BRD4 (D1) and BRD4 (D2) were conducted in a 384-well polystyrene plate. The test compounds were first serially diluted in DMSO and the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2022
Entry Details
US Patent