BDBM576378 N-[6-(5-chloro-1,3-benzoxazol-2-yl)spiro[3.3]heptan-2-yl]-5-(methoxymethyl)furan-2-carboxamide::WO2022112207, Example 9

SMILES COCc1ccc(o1)C(=O)NC1CC2(C1)CC(C2)c1nc2cc(Cl)ccc2o1

InChI Key InChIKey=JDPMVIVPLBGIFH-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 576378   

TargetExternal core antigen(HBVgbn)
F. Hoffmann-La Roche

WIPO
LigandPNGBDBM576378(N-[6-(5-chloro-1,3-benzoxazol-2-yl)spiro[3.3]hepta...)
Affinity DataIC50: 1.02E+3nMAssay Description:Detailed procedures regarding primary human hepatocyte (PHH) HBV natural infection assay are described as below. One tube of frozen PHH (10 million c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2022
Entry Details
WIPO WO2022112207

TargetLarge envelope protein(HBV-D)
F. Hoffmann-La Roche

WIPO
LigandPNGBDBM576378(N-[6-(5-chloro-1,3-benzoxazol-2-yl)spiro[3.3]hepta...)
Affinity DataIC50: 1.58E+3nMAssay Description:Detailed procedures regarding primary human hepatocyte (PHH) HBV natural infection assay are described as below. One tube of frozen PHH (10 million c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2022
Entry Details
WIPO WO2022112207