BDBM577079 4-(8-Cyclopropyl-9-oxo-6,7,8,9-tetrahydropyrido[2′,3′:4,5]pyrrolo[1,2-a]pyrazin-10-yl)-2-fluorobenzonitrile ::US11472805, Example 4
SMILES Fc1cc(ccc1C#N)-c1c2C(=O)N(CCn2c2cccnc12)C1CC1
InChI Key InChIKey=YWTCDMZVTLNYLN-UHFFFAOYSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 577079
Affinity DataIC50: 4.66nMAssay Description:The PDE4A3, PDE4B1, PDE4C1 and PDE4D3 assays use the Scintillation Proximity Assay (SPA) technology to measure the inhibition of human recombinant PD...More data for this Ligand-Target Pair
TargetIsoform 3 of cAMP-specific 3',5'-cyclic phosphodiesterase 4D (hPDE4D3) [50-672](Human)
Pfizer
US Patent
Pfizer
US Patent