BDBM577144 8-Cyclopropyl-10-(4-fluoro-2-methylphenyl)-7,8-dihydropyrido[2',3':4,5]pyrrolo[1,2-a]pyrazin-9(6H)-one::US11472805, Example 49
SMILES Cc1cc(F)ccc1-c1c2C(=O)N(CCn2c2cccnc12)C1CC1
InChI Key InChIKey=LZQQXWXCJOTIAP-UHFFFAOYSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 577144
Affinity DataIC50: 2.71nMAssay Description:The PDE4A3, PDE4B1, PDE4C1 and PDE4D3 assays use the Scintillation Proximity Assay (SPA) technology to measure the inhibition of human recombinant PD...More data for this Ligand-Target Pair
TargetIsoform 3 of cAMP-specific 3',5'-cyclic phosphodiesterase 4D (hPDE4D3) [50-672](Human)
Pfizer
US Patent
Pfizer
US Patent