BDBM577434 ((1-((2-amino-4-oxo-3,4-dihydropyrazolo[1,5-a][1,3,5]triazin-8-yl)methyl)cyclopropoxy)methyl)phosphonic Acid ::US11472826, # 22

SMILES C[C@H](Cc1nnc2c(N)ncnn12)OCP(O)(=O)OP(O)(=O)OP(O)(O)=O

InChI Key InChIKey=OZQTUCOZCAGTIY-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 577434   

TargetGag-Pol polyprotein(HIV-1)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM577434(US11472826, # 22 | ((1-((2-amino-4-oxo-3,4-dihydro...)
Affinity DataIC50: 250nMAssay Description:Recombinant full length HIV-1 Reverse Transcriptase (HIVrt) was purchased from Abcam, catalog #ab63979. The last 385 nucleotide region of the HCV ant...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2022
Entry Details
US Patent