BDBM577551 2-[[3-(1-acetylazetidin-3-yl)oxy-1-methyl-pyrazol-4-yl]amino]-7-[(3R,4R)-4-methyltetrahydrofuran-3-yl]pyrrolo[2,3-d]pyrimidine-6-carbonitrile::WO2022263472, Example 1

SMILES C[C@H]1COC[C@@H]1n1c(cc2cnc(Nc3cn(C)nc3OC3CN(C3)C(C)=O)nc12)C#N

InChI Key InChIKey=VEUQFYBPBFSYCD-SGTLLEGYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 577551   

TargetLeucine-rich repeat serine/threonine-protein kinase 2(Homo sapiens (Human))
Sanofi

WIPO
LigandPNGBDBM577551(2-[[3-(1-acetylazetidin-3-yl)oxy-1-methyl-pyrazol-...)
Affinity DataIC50:  6nMAssay Description:The measurements of the activities were made using a LRRK2-G2019S(human) Kinase activity assay as described hereunder. The potency of compounds was e...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
LigandPNGBDBM577551(2-[[3-(1-acetylazetidin-3-yl)oxy-1-methyl-pyrazol-...)
Affinity DataIC50:  5nMAssay Description:The measurements of the activities were made using a LRRK2-G2019S(human) Kinase activity assay as described hereunder. The potency of compounds was e...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed