BDBM578157 4-oxo-5-phenoxy-1,4-::US11478464, Compound 2

SMILES CCOC(=O)c1cn(cc(Oc2ccccc2)c1=O)-c1cc(ccc1O)C#N

InChI Key InChIKey=BMSVTUXQNZVYTR-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 578157   

TargetProstaglandin G/H synthase 2(Human)
King Faisal University

US Patent
LigandPNGBDBM578157(4-oxo-5-phenoxy-1,4- | US11478464, Compound 2)
Affinity DataIC50: 48nMAssay Description:The inhibitory effects of candidate compounds on COX-1 and COX-2 were determined using COX inhibitor screening test kits, testing each compound's...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2022
Entry Details
US Patent

TargetProstaglandin G/H synthase 1(Human)
King Faisal University

US Patent
LigandPNGBDBM578157(4-oxo-5-phenoxy-1,4- | US11478464, Compound 2)
Affinity DataIC50: 1.22E+4nMAssay Description:The inhibitory effects of candidate compounds on COX-1 and COX-2 were determined using COX inhibitor screening test kits, testing each compound's...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2022
Entry Details
US Patent