BDBM578677 3-[5-fluoro-3- ([1,2,4]triazolo[1,5- a]pyridin-6-yl)pyridin- 2-yl]-3-methoxy-5,5- dimethyl-6- oxocyclohex-1-ene-1- carbonitrile (Enantiomer A)::US11479539, Compound 212

SMILES COC1(CC(C)(C)C(=O)C(=C1)C#N)c1ncc(F)cc1-c1ccc2ncnn2c1

InChI Key InChIKey=KHRBNPYQGAXMKH-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 578677   

Targethek293 luciferase(HIV-1)
Medimmune

US Patent
LigandPNGBDBM578677(US11479539, Compound 212 | 3-[5-fluoro-3- ([1,2,4]...)
Affinity DataEC50:  7nMAssay Description:Purpose of the AssayThe purpose of this assay is to identify small molecule inhibitors of Keap1, preventing Keap1 binding to Nrf2, and thus activatin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2022
Entry Details
US Patent