BDBM578684 3-[5-fluoro-3- (pyridazin-4-yl)pyridin- 2-yl]-3-methoxy-5,5- dimethyl-6- oxocyclohex-1-ene-1- carbonitrile (Enantiomer A)::US11479539, Compound 220

SMILES COC1(CC(C)(C)C(=O)C(=C1)C#N)c1ncc(F)cc1-c1ccnnc1

InChI Key InChIKey=FPDRDMVOJPZQBT-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 578684   

Targethek293 luciferase(HIV-1)
Medimmune

US Patent
LigandPNGBDBM578684(US11479539, Compound 220 | 3-[5-fluoro-3- (pyridaz...)
Affinity DataEC50:  10nMAssay Description:Purpose of the AssayThe purpose of this assay is to identify small molecule inhibitors of Keap1, preventing Keap1 binding to Nrf2, and thus activatin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2022
Entry Details
US Patent