BDBM578685 3-{5-fluoro-5'-[(propan- 2-yl)sulfonyl][3,3'- bipyridin]-2-yl}-3- methoxy-5,5-dimethyl- 6-oxocyclohex-1-ene-1- carbonitrile (Enantiomer A)::US11479539, Compound 221

SMILES COC1(CC(C)(C)C(=O)C(=C1)C#N)c1ncc(F)cc1-c1cncc(c1)S(=O)(=O)C(C)C

InChI Key InChIKey=FHUIQBMYFQSDOD-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 578685   

Targethek293 luciferase(HIV-1)
Medimmune

US Patent
LigandPNGBDBM578685(US11479539, Compound 221 | 3-{5-fluoro-5'-[(propan...)
Affinity DataEC50:  8nMAssay Description:Purpose of the AssayThe purpose of this assay is to identify small molecule inhibitors of Keap1, preventing Keap1 binding to Nrf2, and thus activatin...More data for this Ligand-Target Pair
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Date in BDB:
12/30/2022
Entry Details
US Patent