BDBM578693 3-[5-fluoro-3-(2- methyl[1,2,4]triazolo [1,5-a]pyridin-7- yl)pyridin-2-yl]-3- methoxy-5,5-dimethyl- 6-oxocyclohex-1-ene-1- carbonitrile (Enantiomer A)::US11479539, Compound 229

SMILES COC1(CC(C)(C)C(=O)C(=C1)C#N)c1ncc(F)cc1-c1ccn2nc(C)nc2c1

InChI Key InChIKey=FWTJOVPVRSGIOD-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 578693   

Targethek293 luciferase(HIV-1)
Medimmune

US Patent
LigandPNGBDBM578693(US11479539, Compound 229 | 3-[5-fluoro-3-(2- methy...)
Affinity DataEC50:  10nMAssay Description:Purpose of the AssayThe purpose of this assay is to identify small molecule inhibitors of Keap1, preventing Keap1 binding to Nrf2, and thus activatin...More data for this Ligand-Target Pair
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Date in BDB:
12/30/2022
Entry Details
US Patent