BDBM579192 US11479559, Example 76

SMILES Fc1ccc(cc1NC(=O)Nc1ccc(Oc2ccnc3cc(OCCCN4CCOCC4)c4OCCOc4c23)cc1)C(F)(F)F

InChI Key InChIKey=PCPMSWFLHZKOIF-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 579192   

TargetProto-oncogene tyrosine-protein kinase receptor Ret(Human)
Beijing Scitech-Mq Pharmaceuticals

US Patent
LigandPNGBDBM579192(US11479559, Example 76)
Affinity DataIC50: 50nMAssay Description:The assay is based on the LANCE TR-FRET technology of Perkin Elmer Inc., and the assay method is as follows:1. Dilution of compounds: a total of 11 c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2022
Entry Details
US Patent