BDBM579740 2-(dimethylamino)-N-(4-((5- (3-fluoro-4-hydroxyphenyl)- 1H-pyrazol-3-yl)amino)-3- methylphenyl)acetamide::US11485711, Compound 182

SMILES Cc1cc(NC(=O)CN(C)C)ccc1Nc1cc(-c2ccc(O)c(F)c2)[nH]n1

InChI Key InChIKey=KFAPFUULYUESCX-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 579740   

TargetTRAF2 and NCK-interacting protein kinase(Human)
Korea Research Institute of Chemical Technology

US Patent
LigandChemical structure of BindingDB Monomer ID 579740BDBM579740(US11485711, Compound 182 | 2-(dimethylamino)-N-(4-...)
Affinity DataIC50: 7nMAssay Description:The inhibitory properties of compounds were evaluated with TNIK kinase enzyme system and luminescent ADP-GloFigure US11485711-20221101-P00001 Kinase ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/6/2023
Entry Details
US Patent