BDBM579843 US11485727, Example 2.14::US20260001863, Example 2.14

SMILES CC(=O)N1C[C@H]2CN(C[C@H]2C1)c1ccc(CNc2ccc(OCc3ccc(nc3)C(F)F)nn2)cc1

InChI Key InChIKey=GDSJFCMQPCFYFY-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 579843   

TargetAutotaxin/Lysophosphatidic acid receptor 2(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 579843BDBM579843(US11485727, Example 2.14 | US20260001863, Example ...)
Affinity DataIC50: 4.40nMAssay Description:Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Confirmation testing of small molecules identifie...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/13/2026
Entry Details
US Patent

TargetAutotaxin(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 579843BDBM579843(US11485727, Example 2.14 | US20260001863, Example ...)
Affinity DataIC50: 4.40nMAssay Description:5 nM recombinant ATX (Cayman Chemicals) was supplemented to 50 mM Tris buffer (pH 8.0) containing 3 mM KCl, 1 mM CaCl2, 1 mM MgCl2 0.14 mM NaCl, and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/6/2023
Entry Details
US Patent