BDBM579920 N-((S)- 3-(3,4- dihydro- isoquin- olin- 2(1H)- yl)-2- hydroxy-::US11485731, Example 1BU

SMILES O[C@@H](CNC(=O)N1CCCC(C1)c1ccc(F)cc1)CN1CCc2ccccc2C1

InChI Key InChIKey=KHARBUSEIBEVGF-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 579920   

TargetMethylosome protein 50/Protein arginine N-methyltransferase 5(Human)
Argonaut Therapeutics

US Patent
LigandPNGBDBM579920(US11485731, Example 1BU | N-((S)- 3-(3,4- dihydro-...)
Affinity DataIC50: 12nMAssay Description:A PRMT5 chemiluminescent assay was used to measure the IC50 activity of PRMT5 of the compounds of Examples 1A to 7 above. Biotinylated histone peptid...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/6/2023
Entry Details
US Patent