BDBM579946 2-hydroxy-3-(1,2,3,4- tetrahydro0 isoquinolin-2- yl)propyl 3- phenylpyrrolidine-1- carboxylate::US11485731, Example 3D

SMILES OC(COC(=O)N1CCC(C1)c1ccccc1)CN1CCc2ccccc2C1

InChI Key InChIKey=LUVXBZDRGFIAKS-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 579946   

TargetMethylosome protein 50/Protein arginine N-methyltransferase 5(Human)
Argonaut Therapeutics

US Patent
LigandPNGBDBM579946(US11485731, Example 3D | 2-hydroxy-3-(1,2,3,4- tet...)
Affinity DataIC50: 15nMAssay Description:A PRMT5 chemiluminescent assay was used to measure the IC50 activity of PRMT5 of the compounds of Examples 1A to 7 above. Biotinylated histone peptid...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/6/2023
Entry Details
US Patent