BDBM580169 6-[3-(Trifluoromethyl)morpholin-4-yl]-4-[2-[3-(trifluoromethyl)phenyl]-1H-pyrrolo[2,3-b]pyridin-4-yl]-1H-pyridin-2-one::US11498919, Example 45

SMILES O=c1cc(-c2ccnc3[nH]c(-c4cccc(C(F)(F)F)c4)cc23)cc(N2CCOCC2C(F)(F)F)[nH]1

InChI Key InChIKey=LDLMFSXKVWKENB-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 580169   

TargetPhosphatidylinositol 3-kinase catalytic subunit type 3(Human)
Sprint Bioscience

US Patent
LigandChemical structure of BindingDB Monomer ID 580169BDBM580169(US11498919, Example 45 | 6-[3-(Trifluoromethyl)mor...)
Affinity DataIC50: 34nMAssay Description:Dilution series of compounds of the invention were prepared in DMSO at 100 times the final assay concentration (n1=n0/3 in 10 points). The compounds ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/17/2023
Entry Details
US Patent