BDBM580175 6-[2-(Trifluoromethyl)-1-piperidyl]-4-[2-[5-(trifluoromethyl)-3-pyridyl]-1H-pyrrolo[2,3-b]pyridin-4-yl]-1H-pyridin-2-one::US11498919, Example 58

SMILES O=c1cc(-c2ccnc3[nH]c(-c4cncc(C(F)(F)F)c4)cc23)cc(N2CCCCC2C(F)(F)F)[nH]1

InChI Key InChIKey=LRTZISIKPSKAIP-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 580175   

TargetPhosphatidylinositol 3-kinase catalytic subunit type 3(Human)
Sprint Bioscience

US Patent
LigandChemical structure of BindingDB Monomer ID 580175BDBM580175(US11498919, Example 58 | 6-[2-(Trifluoromethyl)-1-...)
Affinity DataIC50: 7nMAssay Description:Dilution series of compounds of the invention were prepared in DMSO at 100 times the final assay concentration (n1=n0/3 in 10 points). The compounds ...More data for this Ligand-Target Pair
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Date in BDB:
1/17/2023
Entry Details
US Patent