BDBM580178 6-[4-[(4-fluorophenyl)methylsulfonyl]-2-(trifluoromethyl)piperazin-1-yl]-4-(1H-pyrrolo[2,3-b]pyridin-4-yl)-1H-pyridin-2-one::US11498919, Example 65

SMILES O=c1cc(-c2ccnc3[nH]ccc23)cc(N2CCN(S(=O)(=O)Cc3ccc(F)cc3)CC2C(F)(F)F)[nH]1

InChI Key InChIKey=DNRNHHBDLRQHAU-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 580178   

TargetPhosphatidylinositol 3-kinase catalytic subunit type 3(Human)
Sprint Bioscience

US Patent
LigandChemical structure of BindingDB Monomer ID 580178BDBM580178(US11498919, Example 65 | 6-[4-[(4-fluorophenyl)met...)
Affinity DataIC50: 5nMAssay Description:Dilution series of compounds of the invention were prepared in DMSO at 100 times the final assay concentration (n1=n0/3 in 10 points). The compounds ...More data for this Ligand-Target Pair
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Date in BDB:
1/17/2023
Entry Details
US Patent