BDBM580182 4-[2-[4-Ethylsulfonyl-2-(trifluoromethyl)piperazin-1-yl]-6-oxo-1H-pyridin-4-yl]-1H-pyrrolo[2,3-b]pyridine-2-carbonitrile::US11498919, Example 74

SMILES CCS(=O)(=O)N1CCN(c2cc(-c3ccnc4[nH]c(C#N)cc34)cc(=O)[nH]2)C(C(F)(F)F)C1

InChI Key InChIKey=NYYFCAZTWFWZRD-UHFFFAOYSA-N

Data  1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 580182   

TargetPhosphatidylinositol 3-kinase catalytic subunit type 3(Human)
Sprint Bioscience

US Patent
LigandChemical structure of BindingDB Monomer ID 580182BDBM580182(US11498919, Example 74 | 4-[2-[4-Ethylsulfonyl-2-(...)
Affinity DataIC50: 5nMAssay Description:Dilution series of compounds of the invention were prepared in DMSO at 100 times the final assay concentration (n1=n0/3 in 10 points). The compounds ...More data for this Ligand-Target Pair
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Date in BDB:
1/17/2023
Entry Details
US Patent