BDBM580185 4-[2-Oxo-6-[2-(trifluoromethyl)phenyl]-1H-pyridin-4-yl]-1H-pyrrolo[2,3-b]pyridine-2-carbonitrile::US11498919, Example 80

SMILES N#Cc1cc2c(-c3cc(-c4ccccc4C(F)(F)F)[nH]c(=O)c3)ccnc2[nH]1

InChI Key InChIKey=JOVIYZVQVRVMNU-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 580185   

TargetPhosphatidylinositol 3-kinase catalytic subunit type 3(Human)
Sprint Bioscience

US Patent
LigandChemical structure of BindingDB Monomer ID 580185BDBM580185(US11498919, Example 80 | 4-[2-Oxo-6-[2-(trifluorom...)
Affinity DataIC50: 5nMAssay Description:Dilution series of compounds of the invention were prepared in DMSO at 100 times the final assay concentration (n1=n0/3 in 10 points). The compounds ...More data for this Ligand-Target Pair
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Date in BDB:
1/17/2023
Entry Details
US Patent