BDBM580187 6-[4-Methylsulfonyl-2-(trifluoromethyl)piperazin-1-yl]-4-(1H-pyrazolo[3,4-b]pyridin-4-yl)-1H-pyridin-2-one::US11498919, Example 88

SMILES CS(=O)(=O)N1CCN(c2cc(-c3ccnc4[nH]ncc34)cc(=O)[nH]2)C(C(F)(F)F)C1

InChI Key InChIKey=GJZVFKVARNDTAZ-UHFFFAOYSA-N

Data  1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 580187   

TargetPhosphatidylinositol 3-kinase catalytic subunit type 3(Human)
Sprint Bioscience

US Patent
LigandChemical structure of BindingDB Monomer ID 580187BDBM580187(US11498919, Example 88 | 6-[4-Methylsulfonyl-2-(tr...)
Affinity DataIC50: 5nMAssay Description:Dilution series of compounds of the invention were prepared in DMSO at 100 times the final assay concentration (n1=n0/3 in 10 points). The compounds ...More data for this Ligand-Target Pair
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Date in BDB:
1/17/2023
Entry Details
US Patent