BDBM580546 US11498926, Example 267B

SMILES Cc1noc(C)c1-c1cc(Br)c2[nH]c(=O)n3[C@H](COc1c23)c1ccccn1

InChI Key InChIKey=NXXRHSPHVQKNLW-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 580546   

TargetBromodomain-containing protein 4 [58-164](Human)
Incyte

US Patent
LigandPNGBDBM580546(US11498926, Example 267B)
Affinity DataIC50: 100nMAssay Description:Table 11: BRD4-BD1 and BRD4-BD2 assays were conducted in white 384-well polystyrene plate in a final volume of 20 μL for BD1 and 40 μL for ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/17/2023
Entry Details
US Patent

TargetBromodomain-containing protein 4 [353-454](Human)
Incyte

US Patent
LigandPNGBDBM580546(US11498926, Example 267B)
Affinity DataIC50: 100nMAssay Description:Table 12: BRD4-BD1 and BRD4-BD2 assays were conducted in white 384-well polystyrene plate in a final volume of 40 μL for BD1 and 60 μL for ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/17/2023
Entry Details
US Patent