BDBM580707 US11492346, Example 47

SMILES COc1cc(C)ccc1S(=O)(=O)Nc1noc2cc(Cn3cccn3)cc(OC)c12

InChI Key InChIKey=CXLXWUWIWQFDMI-UHFFFAOYSA-N

Data  6 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 580707   

TargetHistone acetyltransferase KAT6A [507-778](Homo sapiens)
Pfizer

US Patent
LigandPNGBDBM580707(US11492346, Example 47)
Affinity DataKi:  0.490nMAssay Description:A. Compound preparation 1. Prepare 10 mM stock solutions in 100% DMSO from solid material 2. Serial dilute 10 mM, 1 mM or 0.1 mM compou...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistone acetyltransferase KAT6A [507-778](Homo sapiens)
Pfizer

US Patent
LigandPNGBDBM580707(US11492346, Example 47)
Affinity DataKi:  1.14nMAssay Description:A. Compound preparation 1. Prepare 10 mM stock solutions in 100% DMSO from solid material 2. Serial dilute 10 mM, 1 mM or 0.1 mM compou...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistone acetyltransferase KAT6B(Homo sapiens)
Pfizer

US Patent
LigandPNGBDBM580707(US11492346, Example 47)
Affinity DataKi:  1.32nMAssay Description:A. Compound preparation 1. Prepare 10 mM stock solutions in 100% DMSO from solid material 2. Serial dilute 10 mM, 1 mM or 0.1 mM compou...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistone acetyltransferase KAT7(Homo sapiens)
Pfizer

US Patent
LigandPNGBDBM580707(US11492346, Example 47)
Affinity DataKi:  40nMAssay Description:A. Compound preparation 1. Prepare 10 mM stock solutions in 100% DMSO from solid material 2. Serial dilute 10 mM, 1 mM or 0.1 mM compou...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistone acetyltransferase KAT5(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM580707(US11492346, Example 47)
Affinity DataKi:  180nMAssay Description:A. Compound preparation 1. Prepare 10 mM stock solutions in 100% DMSO from solid material 2. Serial dilute 10 mM, 1 mM or 0.1 mM compou...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistone acetyltransferase KAT8(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM580707(US11492346, Example 47)
Affinity DataKi:  560nMAssay Description:TBDA. Compound preparation 1. Prepare 10 mM stock solutions in 100% DMSO from solid material 2. Serial dilute 10 mM, 1 mM or 0.1 mM com...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent