BDBM580769 US11492346, Example 114

SMILES COc1cccc(OC)c1S(=O)(=O)Nc1noc2cc(Cc3ccon3)cc(OC)c12

InChI Key InChIKey=IMBIZIMHRANLQL-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 580769   

TargetHistone acetyltransferase KAT6A [507-778](Human)
Pfizer

US Patent
LigandPNGBDBM580769(US11492346, Example 114)
Affinity DataKi:  1.90nMAssay Description:A. Compound preparation 1. Prepare 10 mM stock solutions in 100% DMSO from solid material 2. Serial dilute 10 mM, 1 mM or 0.1 mM compound stocks 3-fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/20/2023
Entry Details
US Patent

TargetHistone acetyltransferase KAT6B(Human)
Pfizer

US Patent
LigandPNGBDBM580769(US11492346, Example 114)
Affinity DataKi:  2nMAssay Description:A. Compound preparation 1. Prepare 10 mM stock solutions in 100% DMSO from solid material 2. Serial dilute 10 mM, 1 mM or 0.1 mM compound stocks 3-fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/20/2023
Entry Details
US Patent

TargetHistone acetyltransferase KAT7(Human)
Pfizer

US Patent
LigandPNGBDBM580769(US11492346, Example 114)
Affinity DataKi:  220nMAssay Description:A. Compound preparation 1. Prepare 10 mM stock solutions in 100% DMSO from solid material 2. Serial dilute 10 mM, 1 mM or 0.1 mM compound stocks 3-fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/20/2023
Entry Details
US Patent