BDBM580933 US11492348, Compound (+)143

SMILES Nc1ncc(cn1)-c1cc(cc(n1)N1CCOCC1)S(=O)(=O)[C@@H]1CCOc2ccccc12

InChI Key InChIKey=ONIJZTXFVDGPGP-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 580933   

TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Human)
Neuropore Therapies

US Patent

LigandBDBM580933(US11492348, Compound (+)143)Copy SMILESCopy InChI

Affinity DataIC50: 4.5nMAssay Description:Quantification of ATP to ADP conversion as a measure of PI3Kα activity. Active PI3Kα (Life Technologies), in the presence or absence of PI3...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
1/20/2023
Entry Details
Copy BDB DOIUS Patent

Copy reaction URL