BDBM580939 5-(6-morpholino-4-((tetrahydro-2H-pyran-4- yl)sulfonyl)pyridin-2-yl)pyrimidin-2-amine::US11492348, Compound 148

SMILES Nc1ncc(cn1)-c1cc(cc(n1)N1CCOCC1)S(=O)(=O)C1CCOCC1

InChI Key InChIKey=ICOKHIMJIZTIGD-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 580939   

TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Human)
Neuropore Therapies

US Patent

LigandBDBM580939(US11492348, Compound 148 | 5-(6-morpholino-4-((tet...)Copy SMILESCopy InChI

Affinity DataIC50: 13nMAssay Description:Quantification of ATP to ADP conversion as a measure of PI3Kα activity. Active PI3Kα (Life Technologies), in the presence or absence of PI3...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
1/20/2023
Entry Details
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