BDBM581353 US11505523, Compound 13c::US11505523, Compound 18d

SMILES COc1ccc(OCCCCOc2cc(OC)ccc2\C=C\C(=O)NO)cc1

InChI Key InChIKey=YYFABWQWBWCRTI-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 581353   

TargetHistone deacetylase 8(Human)
City of Hope

US Patent
LigandPNGBDBM581353(US11505523, Compound 13c | US11505523, Compound 18...)
Affinity DataIC50: 200nMAssay Description:Further provided herein are methods of inhibiting HDAC8 mediated deacetylation of p53. In one aspect, the method includes contacting HDAC8 with a HDA...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/21/2023
Entry Details
US Patent

TargetHistone deacetylase 8(Human)
City of Hope

US Patent
LigandPNGBDBM581353(US11505523, Compound 13c | US11505523, Compound 18...)
Affinity DataIC50: 614nMAssay Description:Further provided herein are methods of inhibiting HDAC8 mediated deacetylation of p53. In one aspect, the method includes contacting HDAC8 with a HDA...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/21/2023
Entry Details
US Patent