BDBM581361 US11505523, Compound 22a

SMILES COc1ccc(\C=C\C(=O)NO)c(c1)-c1ccccc1

InChI Key InChIKey=NCZMYLRFZJDWFS-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 581361   

TargetHistone deacetylase 8(Human)
City of Hope

US Patent
LigandPNGBDBM581361(US11505523, Compound 22a)
Affinity DataIC50: 72.4nMAssay Description:Further provided herein are methods of inhibiting HDAC8 mediated deacetylation of p53. In one aspect, the method includes contacting HDAC8 with a HDA...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/21/2023
Entry Details
US Patent