BDBM581362 US11505523, Compound 22c

SMILES COc1ccc(\C=C\C(=O)NO)c(c1)-c1cccc2ccccc12

InChI Key InChIKey=AQGQYFSOPHFYQU-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 581362   

TargetHistone deacetylase 8(Human)
City of Hope

US Patent
LigandPNGBDBM581362(US11505523, Compound 22c)
Affinity DataIC50: 78nMAssay Description:Further provided herein are methods of inhibiting HDAC8 mediated deacetylation of p53. In one aspect, the method includes contacting HDAC8 with a HDA...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/21/2023
Entry Details
US Patent