BDBM581364 US11505523, Compound 22f

SMILES COc1ccc(\C=C\C(=O)NO)c(c1)-c1ccc(cc1)C(=O)c1ccccc1

InChI Key InChIKey=VBZRCNMHYHLVSL-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 581364   

TargetHistone deacetylase 8(Human)
City of Hope

US Patent
LigandPNGBDBM581364(US11505523, Compound 22f)
Affinity DataIC50: 41.8nMAssay Description:Further provided herein are methods of inhibiting HDAC8 mediated deacetylation of p53. In one aspect, the method includes contacting HDAC8 with a HDA...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/21/2023
Entry Details
US Patent